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<div class="abstract-content selected" id="enc-abstract"> <p> The treatment of homosexual inmates in Nazi concentration camps is a subject which was largely ignored by historians in both West and East Germany after the war. Not until the 1980s, when research began to focus on some of the lesser-known victims of Nazi terror, did attention shift to the fate of homosexuals. This process can be seen clearly at the Buchenwald Memorial in the former GDR, the site of the persecution and also the death of considerable numbers of prisoners identified by the pink triangle on their clothing. The persecution of homosexuals in Nazi Ger…
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Latest: June 10, 2022, 1:05 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> There is an ongoing international discussion on whether the condition reactive arthritis should be named after a former Nazi functionary. The German dermatological community should participate in this debate. In 1916, Hans Reiter described a disease with the symptoms urethritis, conjunctivitis, and arthritis, which was later named after him. After becoming titular professor in May 1918, Reiter was appointed director of the regional public health department Mecklenburg-Schwerin in 1926. At the same time he taught social hygiene at the University of Rostock, where…
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Latest: June 10, 2022, 1:05 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> In scholarly debates, Ludwik Fleck's post-war paper 'Problemy naukoznawstwa [Problems of the Science of Science]', published in 1946, has been taken unanimously to illustrate the epistemology expounded in his monograph Genesis and Development of a Scientific Fact. The paper has also been seen to support parts of the received view of Fleck, notably that he manufactured an anti-typhus vaccine while imprisoned in Buchenwald. However, a different narrative emerges when comparing Fleck's paper with other accounts, also published in 1946 and writte…
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Latest: June 10, 2022, 1:05 a.m.
di Monte) cheered me very much, and I am beginning altogether to look at the future differently. There is one thing I feel really happy about. I see now my actual position towards people, divested of the social advantages I have hitherto held; and I find it a very pleasant one. I don’t think I deceive myself in imagining that people easily like me, and get interested in my ideas, while I find abundance to like and esteem in a large proportion of those I meet.” (Optimism, once more! the reader will say!) It was not, however, “all beer and skittles” for me at the Schiassi pension. I had, as I have mentioned, taken a pretty little room looking out…
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Latest: June 14, 2022, 3:59 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> The Korean Baseball Organization (KBO) League is a sports culture that Koreans love and enjoy most. However, the launch of the KBO League is related to political issues in Korea. The purpose of this study is to explain the launch history of the KBO league through a sociopolitical approach. The history of the KBO league was explained by applying a complex paradigm that explains sociocultural phenomena from a new perspective. This study used historical analysis, a qualitative study approach. Literature related to Korean professional baseball, complex system theory…
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Latest: June 10, 2022, 1:05 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> The first paper describing the pharmacological actions of thalidomide was published in 1956. The drug, then designated as K17, was thought to have sedative effects superior to those of comparator drugs and was thought to be virtually nontoxic. Only 2 years after thalidomide's launch as Contergan in Germany, it's alleged lack of toxicity came into question, with reports of the drug causing numerous side effects. Shortly thereafter, thalidomide was connected with an epidemic of horrific deformities in children whose mothers had taken the drug during preg…
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Latest: June 10, 2022, 1:05 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> This study investigates source-related noise characteristics of the Falcon 9, a modern launch vehicle with a high operational tempo. Empirical prediction of the noise characteristics of launched rockets has long been a topic of study; however, there are relatively few comparisons with high-fidelity, far-field data, and historical inconsistencies persist. Various quantities are considered: overall directivity, overall sound power, maximum overall sound pressure level (OASPL), and peak frequency. The noise directivity of the Falcon 9 vehicle is shown to be between…
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Latest: June 10, 2022, 1:05 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> This report describes a 79-year-old Caucasian man with a history of syringomyelia, paraplegia and a long-term urethral catheter, presenting with recurrent catheter-related or catheter-associated urinary tract infections (CAUTIs) and persistent delirium. On one occasion, urine cultured bacteria from the <i> Burkholderia cepacia </i> complex (BCC). This organism is recognised as being a coloniser of fluid or aquatic settings. However, in certain circumstances (eg, immunosuppression, immunocompromise, multimorbidity), BCC has been recognised to…
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Latest: June 10, 2022, 3:46 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Importance: </strong> The high cost of cancer medicines is a public health challenge. Policy makers in the US and Europe are debating reforms to drug pricing that would cover both the prices of new medicines when entering the market and price increases after they are launched. </p> <p> <strong class="sub-title"> Objective: </strong> To assess launch prices, postlaunch price changes, and clinical benefit of cancer drugs in the US compared with 3 European countries…
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Latest: June 10, 2022, 1:05 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> In the game of softball, the batter should possess the necessary skills to hit the ball toward various directions with high initial speed. However, because various factors influence each other, there are limitations to the range that can be controlled by the batter's skill. This study was aimed at extracting the impact characteristics associated with the launch speed/direction and batted ball spin and clarifying the important skills required to improve the batter's hitting performance. In our experiments, 20 female softball players, who are members of …
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Latest: June 10, 2022, 1:05 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> The InSight (Interior Exploration using Seismic Investigations, Geodesy and Heat Transport) Mars mission launched from Vandenberg Air Force Base on an Atlas V 401 rocket on May 5, 2018. Prior to launch, the InSight spacecraft, associated launch vehicle hardware, and ground support equipment were required to satisfy Planetary Protection requirements to comply with international treaty obligations and demonstrate compliance with National Aeronautics and Space Administration (NASA) levied bioburden requirements. InSight was the first bioburden-controlled mission to…
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Latest: June 10, 2022, 1:05 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Unlike most animals, which form ascorbic acid by metabolizing glucose, humans require an exogenous source. Vitamin C occurs primarily in fruits and vegetables, and scurvy develops from inadequate consumption of these sources, usually because of ignorance about proper nutrition, psychiatric disorders, alcoholism, or social isolation. The earliest symptom of scurvy, occurring only after many weeks of deficient intake, is fatigue. The most common cutaneous findings are follicular hyperkeratosis, perifollicular hemorrhages, ecchymoses, xerosis, leg edema, poor wound…
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Many pathways have been involved in pathophysiology of the fragile X syndrome, one of the more frequent genetic causes of intellectual disability and autism. This review highlights the recent insights in the role the abnormalities in the GABAergic system play in the disorder. Since the initial observations showed that the expression of specific subunits of the GABA(A) receptor were underexpressed in the fragile X knockout mouse model more than a decade ago, evidence has accumulated that the expression of approximately half of the GABAergic system is compromised …
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Childhood type 1 diabetes is increasing globally and requires meticulous at-home care due to risks for fatal outcomes if glucose levels are not continuously and correctly monitored. Type 1 diabetes research has focused on metabolism and stress measurements confirming high parental worry levels. However, research on caregivers' management strategies has lagged. We show parents' intense, all-encompassing work to preempt a disastrous drop in their child's glucose as a stress-path to the virtual embodiment of their child's condition. That is, par…
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Latest: June 11, 2022, 1:56 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Fragile X syndrome (FXS) is the most common single gene disorder, which causes autism and intellectual disability. The fragile X mental retardation 1 (FMR1) gene is silenced when cytosine-guanine-guanine (CGG) triplet repeats exceed 200, which is the full mutation that causes FXS. Carriers of FXS have a CGG repeat between 55 and 200, which is defined as a premutation and transcription of the gene is overactive with high levels of the FMR1 mRNA. Most carriers of the premutation have normal levels of fragile X mental retardation protein (FMRP) and a normal intelli…
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Fragile X Syndrome (FXS) is a genetic disease due to a CGG trinucleotide expansion, named full mutation (greater than 200 CGG repeats), in the fragile X mental retardation 1 gene locus Xq27.3; which leads to an hypermethylated region in the gene promoter therefore silencing it and lowering the expression levels of the fragile X mental retardation 1, a protein involved in synaptic plasticity and maturation. Individuals with FXS present with intellectual disability, autism, hyperactivity, long face, large or prominent ears and macroorchidism at puberty and thereaf…
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Fragile X syndrome (FXS) is the most common cause of inherited intellectual disability and the leading form of the monogenic cause of autism. Fragile X mental retardation type 1 (FMR1) gene premutation is the first single-gene cause of primary ovarian failure (Fragile X-associated primary ovarian insufficiency [FXPOI]) and one of the most common causes of ataxia (fragile X-associated tremor/ataxia syndrome [FXTAS]), multiple additional phenotypes such as fibromyalgia, hypothyroidism, migraine headaches, sleep disturbances, sleep apnea, restless legs syndrome, ce…
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Diseases connected with work in hay have existed in Iceland since its settlement late in the 9th century. Haymaking was probably easier in those days because of better climate and land quality but became more difficult later when these factors deteriorated. First data on diseases connected with hay are from the early 17th century where the word "haysickness" (in Icelandic "heysótt") is used in a book on treatment of diseases. Later in the century the word is found in a rhyme that says "short of breath due to haysickness". The word &…
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Horses suffering from equine asthma must consume low-dust forage, with soaking and steaming being suitable methods of hay treatment. The impacts of this treated hay's subsequent storage and effects on the horses' chewing activity are largely unknown. Meadow hay was soaked (10-15 °C, 15 min) or steamed (100 °C, 60 min). Microbial counts (colony forming units (CFU)) were determined by culture before and after soaking or steaming, and subsequent storage at 10 and 25 °C for 6, 12 and 24 h (three replicates each). Six horses were fed native, soaked and stea…
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Equine peripheral caries (PC) can cause significant dental pathology and appears to be increasing in prevalence and recognition in many areas [1, 2]. Previous studies have identified risk factors for the condition including the feeding of oaten hay [3]. It was hypothesized that this may be due to the higher water soluble carbohydrate (WSC) or "sugar" content of the hay. A randomized control trial involving 30 horses on three properties was completed. The horses were randomly assigned to two groups: high WSC (H-WSC) or low WSC (L-WSC) oaten hay and were…
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> In the last decade, advances in Brazilian hay production showed that the country has the potential to produce bulky dehydrated fodder. For many years, the Brazilian hay production scientific knowledge had been based on temperate climate species, even though the best hay material are tropical grasses, as Tifton 85 Bermudagrass. Researches that focused on the comprehension of yield systems, biochemical processes, physiology, composition, and nutritional quality of tropical species under dehydration and conservation have become important to hay yield in Brazil. The…
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Background: </strong> Equine peripheral caries can cause significant morbidity and can have considerable welfare implications. Recent research suggests that diets with high water soluble carbohydrate (WSC) content are associated with high risk of peripheral caries. Previous work has indicated that the condition may be treatable if the inciting cause is removed and the damaged tooth allowed to erupt out, being replaced by the unaffected tooth previously under the gingival margin. </p> <p> <…
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Photosensitization, also known as photodermatitis, occurs when phototoxic or photoactive substances accumulate in the skin and interact with sunlight to result in an often severe, crusting, itching or painful dermatitis in unpigmented and/or lightly haired areas of the skin. Primary photosensitization, caused by direct ingestion of photosensitizing agents, has been reported anecdotally in horses after ingestion of alfalfa hay. Between 2004 and 2014, several large outbreaks of primary photosensitization in horses fed primarily alfalfa hay were investigated in Cal…
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Latest: June 10, 2022, 1:06 a.m.
for use in after life, even to the lighting of a fire or cooking a potato. Their poor faces were often scarred by disease and half blinded by ophthalmia. The girls wore the hideous workhouse cotton frocks, not half warm enough to keep them healthy in those bare, draughty wards, and heavy hob-nailed shoes which acted like galley-slaves’ bullets on their feet when they were turned to “play” in a high-walled, sunless yard, which was sometimes, as I have seen, six inches deep in coarse gravel. As to the infants, if they happened to have a good motherly matron it was so far well, though even she (mostly busy elsewhere) could do but little to make the c…
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Latest: June 14, 2022, 3:59 a.m.
the registers of entries and departures?” “I do.” “To these registers there are added notes relative to the prisoners?” “There are special reports on every prisoner.” “Well, sir, I was educated at Rome by a poor devil of an abbé, who disappeared suddenly. I have since learned that he was confined in the Château d’If, and I should like to learn some particulars of his death.” “What was his name?” “The Abbé Faria.” “Oh, I recollect him perfectly,” cried M. de Boville; “he was crazy.” “So they said.” “Oh, he was, decidedly.” “Very possibly; but what sort of madness was it?” “He pretended to know of an immense treasure, and o…
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Latest: June 14, 2022, 5:25 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> The COVID-19 crisis is an unprecedented event. It is therefore essential for dispatch centres to share their experiences while the crisis is underway, similar to hospitals, so that we will all benefit from feedback.This letter to the editor describes the Lausanne dispatch centre response to COVID-19 and the lessons learned so far. </p> </div>
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Latest: June 14, 2022, 6:46 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Birds in agricultural environments have exhibited steep global population declines in recent decades, and effective conservation strategies targeting their populations are urgently needed. In grasslands used for hay production, breeding birds' nest success improves substantially if hay harvests are delayed until after mid-July. However, few studies have investigated private hay producers' willingness to alter their harvesting practices, which is a critical factor for bird conservation where most land is privately owned, such as in the North American Gr…
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Experiments were performed to determine the effects of feeding method and hay processing (Experiment 1), energy supplement moisture content and feeding method (Experiment 2), and access time to hay (Experiment 3) on cow body weight ( <b> BW </b> ), dry matter intake ( <b> DMI </b> ), and hay or energy supplement intake and waste. Experiment 1 was designed as a 4 × 4 Latin Square using 48 multiparous, late-gestating, Angus cows (626 kg initial BW). Cows were stratified by age and BW into four treatment groups ( <i>…
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Two experiments were conducted to determine the effects of feeder design on hay intake, apparent diet digestibility, and hay waste in gestating beef cows. Native tallgrass prairie hay and a protein supplement was fed throughout both experiments. In Exp. 1, 56 crossbred cows were used in a Latin square arrangement. Feeder design treatments included a conventional open bottom steel ring ( <b> OBSR </b> ), an open bottom polyethylene pipe ring ( <b> POLY </b> ); a sheeted bottom steel ring ( <b> RING </b>…
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Diseases connected with work in hay have been known in Iceland for a long time. In 1981 scientific studies of these diseases were started in Iceland at the request of the Farmers Union. The results of these studies are summarized in this article. In studies of hay a great amount of storage mites, moulds and thermophilic actinomycetes (microlyspora faeni) were found in addition to allergens from mice and pollen. Symptoms caused by hay dust were mainly from nose and eyes in people with positive skin tests, but cough, dyspnea and fever were equally common in those …
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Latest: June 10, 2022, 1:06 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Regeneration of lost body parts is essential to regain the fitness of the organism for successful living. In the animal kingdom, organisms from different clades exhibit varied regeneration abilities. Hydra is one of the few organisms that possess tremendous regeneration potential, capable of regenerating complete organism from small tissue fragments or even from dissociated cells. This peculiar property has made this genus one of the most invaluable model organisms for understanding the process of regeneration. Multiple studies in Hydra led to the current unders…
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Latest: June 10, 2022, 1:07 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Hydra, a Cnidarian believed to have been evolved about 60 million years ago, has been a favorite model for developmental biologists since Abraham Trembley introduced it in 1744. However, the modern renaissance in research on hydra was initiated by Alfred Gierer when he established a hydra laboratory at the Max Plank Institute in Göttingen in the late 1960s. Several signaling mechanisms that regulate development and pattern formation in vertebrates, including humans, have been found in hydra. These include Wnt, BMP, VEGF, FGF, Notch, and RTK signaling pathways. W…
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Latest: June 10, 2022, 1:07 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> The convergence of morphogenesis into viable organisms under variable conditions suggests closed-loop dynamics involving multiscale functional feedback. We develop the idea that morphogenesis is based on synergy between mechanical and bio-signaling processes, spanning all levels of organization: molecular, cellular, tissue, up to the whole organism. This synergy provides feedback within and between all levels of organization, to close the loop between the dynamics of the morphogenesis process and its robust functional outcome. Hydra offer a powerful platform to …
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Latest: June 10, 2022, 1:07 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> <i> Hydra vulgaris </i> is an emerging model organism for neuroscience due to its small size, transparency, genetic tractability, and regenerative nervous system; however, fundamental properties of its sensorimotor behaviors remain unknown. Here, we use microfluidic devices combined with fluorescent calcium imaging and surgical resectioning to study how the diffuse nervous system coordinates <i> Hydra </i> 's mechanosensory response. Mechanical stimuli cause animals to contract, and we find this response relies on at …
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Latest: June 10, 2022, 1:07 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Hydra have been extensively used for studying the teratogenic and toxic potential of numerous toxins throughout the years and are more recently growing in popularity to assess the impacts of environmental pollutants. Hydra are an appropriate bioindicator species for use in environmental assessment owing to their easily measurable physical (morphology), biochemical (xenobiotic biotransformation; oxidative stress), behavioural (feeding) and reproductive (sexual and asexual) endpoints. Hydra also possess an unparalleled ability to regenerate, allowing the assessmen…
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Latest: June 10, 2022, 1:07 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Polledness has been shown to have autosomal Mendelian inheritance, with the polled locus being dominant to the horned locus. This trait was mapped to the BTA1 centromeric end in several breeds. One of the distinctive attributes of Creole cattle, such as the Argentinean Creole, is the presence of long, lyre-shaped horns. However, polled native animals were reported before the introduction of modern selected European breeds. Here, we studied the origin of the polled mutation, either independent or introgressed, in a Creole line from the Creole cattle founder group…
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Latest: June 10, 2022, 1:07 a.m.
Burntisland. Writing from thence to Miss Elliot about her own country, and countrymen, I said:— “I came here to look up the scene of Mrs. Somerville’s childhood, and I have found everything just as she described it;—the Links; the pretty hills and woods full of wild flowers; the rocky bit of shore with boulders full of fossil shells which excited her childish wonder when she wandered about, a beautiful little girl, as she must have been. If ever there were a case of— “‘Nourishing a youth sublime, With the fairy tales of science and the long results of Time,’ it was surely hers. Very naturally I was thinking of her…
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Latest: June 14, 2022, 3:59 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> The genetic diversity of the BoLA-DRB3 gene has been reported in different cattle breeds owing to its central role in the immune response. However, it is still unknown in hundreds of cattle breeds, especially native populations. Here, we studied BoLA-DRB3 genetic diversity in Highland Creole cattle (CrAl) from Western Bolivia, raised at altitudes between 3800 and 4200 m. DNAs from 48 CrAl cattle were genotyped for BoLA-DRB3 exon 2 alleles using polymerase chain reaction-sequence-based typing (PCR-SBT). The results were compared with 1341 previously reported data…
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Latest: June 10, 2022, 1:07 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> To establish the diversity, structure, and phylogenetic relationships among Colombian Creole cattle, six native breeds and one introduced breed were genotyped for 20 microsatellite loci. The average number of alleles per breed ranged from 7050 (Romosinuano) to 10,100 (Casanareño), and the expected heterozygosity ranged from 0.691 (San martinero) to 0.785 (Casanareño). The deviation from the Hardy-Weinberg equilibrium (HWE) was statistically significant (p &lt; 0.05) in 59 out of 120 tests carried out in the six breeds for the 20 microsatellite loci analyzed.…
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Latest: June 10, 2022, 1:07 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Purpose The purpose of this study is to characterize narrative competence of typically developing bilingual children using Jamaican Creole (JC) and English. Method Story comprehension and fictional storytelling tasks in JC and English were completed by 104 bilingual preschoolers aged 4-6 years. Story comprehension was analyzed using inferential story comprehension questions representing Blank's Question Hierarchy. Fictional storytelling was analyzed using the Monitoring Indicators of Scholarly Language framework for narrative macrostructure and microstructu…
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Latest: June 10, 2022, 1:07 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Characterization of Creole breeds is still very limited, including reproductive performance. In this research, we assessed the semen quality of three Colombian Creole breeds (Zungo, Casco de Mula and San Pedreño) relative to that of international breeds (Duroc, Belgian Landrace and Pietrain). Two doses from seven boars per breed were evaluated for sperm kinetics and membrane and acrosome integrity using computer-assisted sperm analysis (CASA) and flow cytometry, respectively. The Creole pigs showed lower (P &lt; 0.05) volume of fluid ejaculated (185.5 mL vs …
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Latest: June 10, 2022, 1:07 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> In the framework of the GreenEdge Project (whose the general objective is to understand the dynamic of the phytoplankton spring bloom in Arctic Ocean), lipid composition and viability and stress state of bacteria were monitored in sea ice and suspended particulate matter (SPM) samples collected in 2016 along a transect from sea ice to open water in Baffin Bay (Arctic Ocean). Lipid analyses confirmed the dominance of diatoms in the bottommost layer of ice and suggested (i) the presence of a strong proportion of micro-zooplankton in SPM samples collected at the we…
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Latest: June 10, 2022, 1:08 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Background: </strong> Dynamic rehabilitation of longstanding facial palsy with damaged, atrophied, or absent facial muscles requires replacement of neural and muscular components. The ideal reconstruction would include a fast-twitch muscle that is small, a reliable donor vessel and nerve, and the potential to provide a natural, synchronous, dentate smile with minimal donor site morbidity. Many flaps have been successfully used historically, but none has produced ideal rehabilitation. </p> <p> …
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Latest: June 10, 2022, 1:07 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Postoperative sterno-mediastinitis is a life-threatening complication that occurs in about 0.75 to 1.4 per cent of all open heart operations. The result of treatment largely depends on timely diagnosis and appropriate surgical management. Risk factors for infection should be corrected preoperatively whenever possible. Among other preventive measures, meticulous asepsis, atraumatic surgical technique, preserving the blood supply and the mechanical integrity of the sternum, prevention of sternal instability, and correction of the same if it occurs are the most imp…
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Latest: June 10, 2022, 1:07 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> With an incidence rate of 1-4%, mediastinitis following cardiac surgery is a rarely occurring complication, but may show a mortality rate of up to 50%. Risk factors for sternal instability are insulin-dependent diabetes mellitus, obesity, immunosuppressed state, chronic obstructive pulmonary disease, osteoporosis, history of radiation, renal failure, body height, smoking and nutritional state. The aim of this paper is to show an overview of this clinical picture, present the risk factors and elucidate the therapy options chronologically. As a result of interdisc…
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Latest: June 10, 2022, 1:07 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Aim: </strong> To analyze clinical course and develop surgical technique for thoracoabdominal hernia in patients after previous sterno-mediastinitis. </p> <p> <strong class="sub-title"> Material and methods: </strong> There were 7 (20%) patients aged 53-69 years with thoracoabdominal hernia after previous cardiac surgery followed by postoperative sterno-mediastinitis. Thoracoomentoplasty was used for treatment of this complication. There were 2 males and 5 female…
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<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Background: </strong> Anastomotic leakage (AL) is a serious complication after esophagectomy. The retrosternal (RS) route has been selected majorly to reduce reflux and related pneumonia and considering mediastinal recurrences. AL has been developed more in RS than posterior mediastinal (PM) route reconstruction. Therefore, we suspected the sterno-tracheal distance (STD) might be related to AL and started the selection according to the STD from 2009. </p> <p> <strong class="sub-title…
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<div class="abstract-content selected" id="enc-abstract"> <p> Organic microfossils in Meso- and Neoproterozoic rocks are of key importance to track the emergence and evolution of eukaryotic life. An increasing number of studies combine Raman spectroscopy with synchrotron-based methods to characterize these microfossils. A recurring observation is that Raman spectra of organic microfossils show negligible variation on a sample scale and that variation between different samples can be explained by differences in thermal maturation or in the biologic origin of organic precursor material. There is a paucity of work, however, t…
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<div class="abstract-content selected" id="enc-abstract"> <p> Seismic surveys increasingly operate in deeper Arctic waters with propagation conditions and marine mammal fauna different from the better-studied temperate, or shallow-water, regions. Using 31 calibrated sound recorders, we quantified noise contributions from four concurrent seismic surveys in Baffin Bay, Greenland, to estimate their potential impacts on marine mammals. The impact was cumulative as the noise level rose in response to the onset of each survey: on a minute-by-minute scale the sound-exposure-levels varied by up to 70 dB (20 dB on average), dependi…
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<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Background: </strong> The Children's Hospital of Eastern Ontario (CHEO) provides services to children in Baffin Island, through the Baffin Island Pediatric Health Initiative. Tuberculosis (TB) remains a major public health problem in that region. The objective of our study was to describe the origin and clinical characteristics of patients with TB disease at CHEO, since the inception of the Baffin Island Pediatric Health Initiative. </p> <p> <strong class="sub-title"> …
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<div class="abstract-content selected" id="enc-abstract"> <p> Once limited to the Laguna Madre of Texas, blooms of the brown tide organism, Aureoumbra lagunensis, have recently been reported elsewhere. Previous studies have focused on the role of extreme hypersalinity and lack of grazing pressure as facilitators of brown tide blooms. However, development of blooms in systems that are not experiencing extreme hypersalinity, and also that are undergoing eutrophication, suggests that our understanding of A. lagunensis bloom dynamics requires additional refinement. The goal of this study was to quantify the spatial-temporal di…
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<div class="abstract-content selected" id="enc-abstract"> <p> Global climate change is expected to alter the polar bioregions faster than any other marine environment. This study assesses the biodiversity of seaweeds and associated eukaryotic pathogens of an established study site in northern Baffin Island (72° N), providing a baseline inventory for future work assessing impacts of the currently ongoing changes in the Arctic marine environment. A total of 33 Phaeophyceae, 24 Rhodophyceae, 2 Chlorophyceae, 12 Ulvophyceae, 1 Trebouxiophyceae, and 1 Dinophyceae are reported, based on collections of an expedition to the area i…
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<div class="abstract-content selected" id="enc-abstract"> <p> OBJECTIVE. Although infants living in the north of Canada have been reported to have one of the highest rates of hospital admission for bronchiolitis in the world, the economic effects of this condition have not been reported. Passive immunization against the Respiratory Syncytial Virus, the most common causative agent of infant bronchiolitis, is available. </p> <p> <strong class="sub-title"> Methods: </strong> We tabulated transportation, in-hospital care and family accommodation costs for infants of less than 12 mon…
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<div class="abstract-content selected" id="enc-abstract"> <p> Seabed hydrocarbon seeps present natural laboratories for investigating responses of marine ecosystems to petroleum input. A hydrocarbon seep near Scott Inlet, Baffin Bay, was visited for in situ observations and sampling in the summer of 2018. Video evidence of an active hydrocarbon seep was confirmed by methane and hydrocarbon analysis of the overlying water column, which is 260 m at this site. Elevated methane concentrations in bottom water above and down current from the seep decreased to background seawater levels in the mid-water column &gt;150 m above…
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<div class="abstract-content selected" id="fra-abstract"> <p> <strong class="sub-title"> Objectif: </strong> Présenter un cadre clinique afin de prendre en considération les éléments sociaux critiques pour les patients autochtones atteints de diabète de type 2. SOURCES DE L’INFORMATION: Le Cadre de soins fondé sur l’éducation pour l’équité (Educating for Equity [E4E] Care Framework) a été produit à la suite de l’analyse rigoureuse d’une recherche qualitative portant sur les points de vue de patients autochtones (n = 32), de médecins (n = 28) et d’élaborateurs de cursus en santé autochtone (n = …
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<div class="abstract-content selected" id="fra-abstract"> <p> <strong class="sub-title"> Objectif: </strong> Formuler des lignes directrices fondées sur les données probantes afin d’aider les cliniciens à décider du moment et de la façon sécuritaire de réduire la dose des antihyperglycémiants, de mettre fin au traitement ou de passer à un autre agent chez les personnes âgées. MÉTHODES: Nous nous sommes concentrés sur les données les plus probantes disponibles et avons cherché à obtenir les commentaires des professionnels de première ligne durant le processus de rédaction, de révision et d’adopt…
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sis “Mr. Briggs” broke in furiously, bidding the keeper to stop stroking his bird: “Be hanged to you! If you go on like that, you’ll rub it down to a wren!” The creed of many persons in these days seems to be undergoing the process of being patted and praised, while all the time it is being rubbed down to a wren! But whatever hard things Mr. Arnold said of me, I liked and admired him, and he was always personally most kind to me. He had of all men I have ever known the truest insight,—the true _Poet’s_ insight,—into the feelings and characters of animals, especially of dogs. His poem, _Geist’s Grave_, is to me the most affecting description of th…
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learn to write. The same evening, when the flock was safe at the farm, the little Luigi hastened to the smith at Palestrina, took a large nail, heated and sharpened it, and formed a sort of stylus. The next morning he gathered an armful of pieces of slate and began. At the end of three months he had learned to write. The curate, astonished at his quickness and intelligence, made him a present of pens, paper, and a penknife. This demanded new effort, but nothing compared to the first; at the end of a week he wrote as well with this pen as with the stylus. The curate related the incident to the Count of San-Felice, who sent for the little shepherd, m…
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Latest: June 14, 2022, 5:26 a.m.
e entered it. Here began a new epoch in his life. Let us hear him speak himself, as he afterwards confessed to his spiritual adviser, and before the court. “I entered the fortification,” he said, “as an erring man, and I left it--a villain. I had still possessed something in the world which was dear to me, and my pride had bowed down under shame. When I was brought to the fortification, I was confined with three and twenty prisoners, two of whom were murderers, while all the rest were notorious thieves and vagabonds. They scoffed at me, when I spoke of God, and encouraged me to utter all sorts of blasphemies against the Redeemer. Obscene son…
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Latest: June 14, 2022, 6:46 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Contexte: </strong> Étant donné que les maladies oculaires avant l'âge de 5 ans sont courantes, une certaine forme de dépistage des troubles de la vision devrait être effectuée chez les enfants avant qu'ils ne fréquentent l'école primaire. Cependant, l'absence de recommandations nationales cohérentes crée de la confusion chez les patients, les professionnels des soins oculovisuels et les gouvernements. MéTHODES: L'objectif de ce document est de fournir des recommandations quant aux …
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<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Purpose: </strong> During anesthesiologists' careers, a leave of absence (LOA) is common. After prolonged leave, updating may be beneficial in reducing concerns about knowledge and skill decrements. Although formal return-to-work (RTW) courses and checklists assist UK practitioners, and Australia mandates a one-month RTW program for each year away from practice, no Canadian RTW programs exist. This project aimed to determine the needs of anesthesiologists for an RTW program. </p> <p> &l…
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<div class="abstract-content selected" id="enc-abstract"> <p> Time-varying neurophysiological activity has been classically explored using correlation based sliding window analysis. However, this method employs only lower order statistics to track dynamic functional connectivity of the brain. We introduce recursive dynamic functional connectivity (rdFC) that incorporates higher order statistics to generate a multi-order connectivity pattern by analyzing neurophysiological data at multiple time scales. The technique builds a hierarchical graph between various temporal scales as opposed to traditional approaches that analyze…
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<div class="abstract-content selected" id="enc-abstract"> <p> An emerging field of human brain imaging deals with the characterization of the connectome, a comprehensive global description of structural and functional connectivity within the human brain. However, the question of how functional and structural connectivity are related has not been fully answered yet. Here, we used different methods to estimate the connectivity between each voxel of the cerebral cortex based on functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) data in order to obtain observer-independent functional-structural con…
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<div class="abstract-content selected" id="enc-abstract"> <p> In the present study, we examined how morphemic ambiguity is resolved using the visual-world paradigm. Participants were presented with Chinese bimorphemic words containing an ambiguous morpheme (analogous to the suffix -er in teacher and taller) and performed a visual search task. Their eye-movement patterns during target detection showed that (1) without a prior context, the dominant meaning of an ambiguous morpheme was more available than the subordinate one; (2) with a dominant-biased prior context, the subordinate meaning was still activated; and (3) a subo…
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Latest: June 14, 2022, 12:36 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> The study of complex brain networks, where structural or functional connections are evaluated to create an interconnected representation of the brain, has grown tremendously over the past decade. Much of the statistical network science tools for analyzing brain networks have been developed for cross-sectional studies and for the analysis of static networks. However, with both an increase in longitudinal study designs, as well as an increased interest in the neurological network changes that occur during the progression of a disease, sophisticated methods for lon…
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<div class="abstract-content selected" id="enc-abstract"> <p> Analyzing the structure and function of the brain from a network perspective has increased considerably over the past two decades, with regional subnetwork analyses becoming prominent in the recent literature. However, despite the fact that the brain, as a complex system of interacting subsystems (i.e., subnetworks), cannot be fully understood by analyzing its constituent parts as independent elements, most studies extract subnetworks from the whole and treat them as independent networks. This approach entails neglecting their interactions with other brain regio…
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<div class="abstract-content selected" id="enc-abstract"> <p> The network architecture of functional connectivity within the human brain connectome is poorly understood at the voxel level. Here, using resting state functional magnetic resonance imaging data from 1003 healthy adults, we investigate a broad array of network centrality measures to provide novel insights into connectivity within the whole-brain functional network (i.e., the functional connectome). We first assemble and visualize the voxel-wise (4 mm) functional connectome as a functional network. We then demonstrate that each centrality measure captures differ…
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<div class="abstract-content selected" id="enc-abstract"> <p> The human brain is a complex network. An important first step toward understanding the function of such a network is to map its elements and connections, to create a comprehensive structural description of the network architecture. This paper reviews current empirical efforts toward generating a network map of the human brain, the human connectome, and explores how the connectome can provide new insights into the organization of the brain's structural connections and their role in shaping functional dynamics. Network studies of structural connectivity obtai…
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<div class="abstract-content selected" id="enc-abstract"> <p> A growing body of research has suggested that people with schizophrenia (SZ) exhibit altered patterns of functional and anatomical brain connectivity. For example, many previous resting state functional connectivity (rsFC) studies have shown that, compared to healthy controls (HC), people with SZ demonstrate hyperconnectivity between subregions of the thalamus and sensory cortices, as well as hypoconnectivity between subregions of the thalamus and prefrontal cortex. In addition to thalamic findings, hypoconnectivity between cingulo-opercular brain regions though…
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will be renamed. Creating the works from public domain print editions means that no one owns a United States copyright in these works, so the Foundation (and you!) can copy and distribute it in the United States without permission and without paying copyright royalties. Special rules, set forth in the General Terms of Use part of this license, apply to copying and distributing Project Gutenberg-tm electronic works to protect the PROJECT GUTENBERG-tm concept and trademark. Project Gutenberg is a registered trademark, and may not be used if you charge for the eBooks, unless you receive specific permission. If you do not charge anything for copi…
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Latest: June 14, 2022, 12:36 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Recently, a combination of non-invasive neuroimaging techniques and graph theoretical approaches has provided a unique opportunity for understanding the patterns of the structural and functional connectivity of the human brain (referred to as the human brain connectome). Currently, there is a very large amount of brain imaging data that have been collected, and there are very high requirements for the computational capabilities that are used in high-resolution connectome research. In this paper, we propose a hybrid CPU-GPU framework to accelerate the computation…
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<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Background: </strong> Echinoderms and hemichordates are sister taxa that both have larvae with tripartite coeloms. Hemichordates inherit the coelom plan and ectoderm from larvae, whereas echinoderms form the adult rudiment comprising rearranged coeloms and a vestibule that then develops into adult oral ectoderm. Molecular networks that control patterns of the ectoderm and the central nervous system along the anteroposterior (AP) axis are highly conserved between hemichordates and chordates, respectively. In…
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<div class="abstract-content selected" id="enc-abstract"> <p> The aim of this study was to highlight the roles of perlecan in the regulation of the development of the rudiment developmental cartilages and growth plate cartilages, and also to show how perlecan maintains permanent articular cartilage homeostasis. Cartilage rudiments are transient developmental templates containing chondroprogenitor cells that undergo proliferation, matrix deposition, and hypertrophic differentiation. Growth plate cartilage also undergoes similar changes leading to endochondral bone formation, whereas permanent cartilage is maintained as an a…
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<div class="abstract-content selected" id="enc-abstract"> <p> Indirect-developing sea urchins eventually form an adult rudiment on the left side through differential left-right development in the late larval stages. Components of the adult rudiment, such as the hydropore canal, the hydrocoel and the primary vestibule, all develop on the left side alone, and are the initial morphological traits that exhibit left-right differences. Although it has previously been shown that partial embryos dissected in cleavage stages correctly determine the normal left-right placement of the adult rudiment, the timing and the mechanism that…
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<div class="abstract-content selected" id="enc-abstract"> <p> Poly(d,l-lactide-co-glycolide) (PLGA) has been extensively explored for bone regeneration applications; however, its clinical use is limited by low osteointegration. Therefore, approaches that incorporate osteoconductive molecules are of great interest. Graphene oxide (GO) is gaining popularity for biomedical applications due to its ability to bind biological molecules and present them for enhanced bioactivity. This study reports the preparation of PLGA microparticles via Pickering emulsification using GO as the sole surfactant, which resulted in hybrid micropar…
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uins, dominoes, mummers, pantomimists, Transteverins, knights, and peasants, screaming, fighting, gesticulating, throwing eggs filled with flour, confetti, nosegays, attacking, with their sarcasms and their missiles, friends and foes, companions and strangers, indiscriminately, and no one took offence, or did anything but laugh. Franz and Albert were like men who, to drive away a violent sorrow, have recourse to wine, and who, as they drink and become intoxicated, feel a thick veil drawn between the past and the present. They saw, or rather continued to see, the image of what they had witnessed; but little by little the general vertigo seized th…
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Latest: June 14, 2022, 5:26 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Quackery in medicine is as old as medicine itself. In times of crisis, desperate patients often believe extraordinary claims. In the annals of pain-killer quack medicine, snake oil, elixirs, nostrums and Indian liniments hold a special position. NYU College of Dentistry (NYUCD) has a collection of 234 bottles of such medicines dating from the mid-1800s through 1940. This paper is the fifth in a series of articles featuring "Elixirs of the Past" in which we bring to light six more samples with claims to traditional Chinese or American Indian medicine us…
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<div class="abstract-content selected" id="enc-abstract"> <p> Diabetic infection is a long-term complication difficult to cure. The skin of diabetic patients is prone to damage, the healing is slow after the injury, and the wound occurs repeatedly. Therefore, there is an urgent need to develop an effective method for treating diabetes wounds. In this study, we used the electrospinning technique to load Huangbai Liniment (Compound Phellodendron Liquid, CPL) into Silk fibroin (SF) /poly-(L-lactide-co-caprolactone) (PLCL) to prepare the nanofiber membrane (SP/CPL) to treat the diabetic wound. The morphology and structure of t…
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<div class="abstract-content selected" id="enc-abstract"> <p> Atopic dermatitis (AD), also known as atopic eczema, is one of the most common skin diseases and is characterized by allergic skin inflammation, redness, and itchiness and is associated with a hyperactivated type 2 immune response. The leading causes of AD include an imbalance in the immune system, genetic predisposition, or environmental factors, making the development of effective pharmacotherapies complex. Steroids are widely used to treat AD; however, they provide limited efficacy in the long term and can lead to adverse effects. Thus, novel treatments that …
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<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Background: </strong> Lymphangioleiomyomatosis (LAM) is a rare disease that almost exclusively affects women of reproductive age. Patients are warned of the increased risks if they become pregnant. However, information on pregnancy in patients after the diagnosis of LAM is limited. </p> <p> <strong class="sub-title"> Methods: </strong> Patients were collected from the LAM registry study at Peking Union Medical College Hospital, Beijing, China. Patients with a his…
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<div class="abstract-content selected" id="enc-abstract"> <p> Diabetic ulcer is a challenging complication of diabetes mellitus but current treatments cannot achieve satisfactory results. In this study, the effect of Huangbai liniment (HB) and berberine on the wound healing in high fat diet/streptozotocin injection induced diabetic rats was investigated by RNA-seq technology. HB topical treatment promoted wound healing in the diabetic patients and diabetic rats, and it affected multiple processes, of which IL-17 signalling pathway was of importance. Inhibiting IL-17a by its inhibitor or antibody remarkably facilitated woun…
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<div class="abstract-content selected" id="enc-abstract"> <p> Quackery in medicine is as old as medicine itself. In times of crisis, desperate patients often believe extraordinary claims. In the annals of pain-killer quack medicine, elixirs, nostrums and liniments hold a prominent position. NYU College of Dentistry (NYUCD) has a collection of 234 bottles of such medicines dating from the mid-1800s through 1940. This paper is the second in a series of articles featuring "Elixirs of the Past" in which we bring to light five more samples containing opium: <i> Dr. B.J. Kendall's Instant Relief for Pai…
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<div class="abstract-content selected" id="enc-abstract"> <p> As a serious complication of diabetes, nonhealing skin ulcer leads to high mortality and disability in diabetic patients. However, limited therapy is available in managing diabetic wounds. In this study, RNA-seq technology was used to systematically investigate the effect of Huangbai (HB) liniment, a traditional Chinese medicine, on the streptozotocin- (STZ-) induced diabetic wound. HB liniment significantly accelerated the wound closure and enhanced the generation of extracellular matrix in diabetic rats, and oxidative stress was identified to play a vital role…
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<div class="abstract-content selected" id="enc-abstract"> <p> Quackery in medicine is as old as medicine. In times of crisis desperate patients believe in extraordinary claims. In the annals of pain killer quack medicine, elixirs, nostrums and liniments hold a special position. The College of Dentistry at NYU received a collection of 234 bottles of quack medicine dating from approximately 1850 through 1940. </p> <p> In this paper, the THIRD in a series of articles featuring "Elixirs of the Past", we focus on five particularly notable samples claiming to have "electric" properties: <…
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<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Background: </strong> Current eligibility criteria for urine lateral-flow lipoarabinomannan assay (LF-LAM) in ambulatory, HIV-positive patients rely on the CD4 count. We investigated the diagnostic yield of LF-LAM and the 6-month mortality in ambulatory, TB symptomatic, HIV-positive patients regardless of their CD4 count. </p> <p> <strong class="sub-title"> Methods: </strong> We conducted a prospective, observational study that included all ambulatory, ≥15-year-o…
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<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Background: </strong> Tuberculosis (TB) and malnutrition are important causes of morbidity and mortality in children in the developing world. </p> <p> <strong class="sub-title"> Aims: </strong> To assess the prevalence of pulmonary TB in severely malnourished children and evaluate TB detection using the urine lipoarabinomannan antigen assay (TB-LAM). </p> <p> <strong class="sub-title"> Methods: </strong> A retrospectiv…
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<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Ethnopharmacological relevance: </strong> The genus Thymus is among the most important genera in the Lamiaceae family with 215 species and is widely distributed globally, mainly in the Mediterranean region. The genus contains many medicinal plants used in traditional Moroccan medicine for a long time in treating diverse diseases. </p> <p> <strong class="sub-title"> Aim of the review: </strong> This review describes the traditional uses, biological activities and …
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<div class="abstract-content selected" id="enc-abstract"> <p> To maximize tumor resection and minimize postoperative neurological sequelae, intraoperative Direct Electrical Stimulation (DES) coupled with preoperative Navigated Transcranial Magnetic Stimulation (nTMS) is adopted as a more valid procedure when a tumor is located in or near language-positive cortical and subcortical brain areas/networks. To map language functions peri- and intraoperatively, naming tasks are usually administered given their sensitivity and practicality in mapping language networks and their association with positive postoperative outcomes. Lin…
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<div class="abstract-content selected" id="enc-abstract"> <p> The recreational use of nitrous oxide (N2O; laughing gas) has largely expanded in recent years. Although incidental use of nitrous oxide hardly causes any health damage, problematic or heavy use of nitrous oxide can lead to serious adverse effects. Amsterdam care centres noticed that Moroccan-Dutch young adults reported neurological symptoms, including severe paralysis, as a result of problematic nitrous oxide use. In this qualitative exploratory study, thirteen young adult Moroccan-Dutch excessive nitrous oxide users were interviewed. The determinants of proble…
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<div class="abstract-content selected" id="enc-abstract"> <p> A labor and delivery nurse describes the moments of grace that have sustained her during the COVID-19 pandemic. </p> </div>
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that made him hot, his mind was also labouring under a burden of heavy recollections. At last, after the pathway had long vanished from beneath his feet, he came to a beautiful, smooth, dark spot, among some mighty oak-trees. Still he heard his name called in the distance. ‘Here,’ he said, ‘the rude sound yonder will no more reach me; here I shall be quietly concealed.’ He sunk down upon a great mossy stone, his heart heaved, he was struggling with a powerful desire. ‘Forgive my presumption, great master,’ he cried, ‘but there is a knowledge which must be followed by action, otherwise it crushes a mortal. Here, nearer to the heart of the grea…
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al analysis of the faculty of language shews, that even the smallest proficiency in it might require more brain power than the greatest proficiency in any other direction.” He has invented and is able to use various weapons, tools, traps, etc., with which he defends himself, kills or catches prey, and otherwise obtains food. He has made rafts or canoes for fishing or crossing over to neighbouring fertile islands. He has discovered the art of making fire, by which hard and stringy roots can be rendered digestible, and poisonous roots or herbs innocuous. This discovery of fire, probably the greatest ever made by man, excepting language, dates from be…
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Latest: June 15, 2022, 11 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> The number of circulating lymphocytes is altered in a number of diseases including either increase (lymphocytosis) or decrease (lymphocytopenia). Therefore, the assessment of total blood lymphocyte numbers and the relative distribution of lymphocyte subsets is a critical front-line tool in the clinical diagnosis of a number of diseases, including pediatric diseases and disorders. However, the interpretation of this data requires comparison of patient's results to reliable reference values. Blood lymphocyte subpopulation numbers are also subject to genetic p…
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<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Objective: </strong> Cultural adaptation of the tinnitus handicap inventory questionnaire to the Moroccan dialect version. </p> <p> <strong class="sub-title"> Method: </strong> We conducted a prospective study over a 3 years period (January 2017-January 2020) in the Otolaryngology Department of Casablanca University hospital. Translation was produced by a forward-backward procedure with analysis of the psychometric properties of the Moroccan version of the tinnit…
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<div class="abstract-content selected" id="enc-abstract"> <p> Tuberculosis (TB) is a serious infectious disease that kills approximately two million people per year, particularly in low- and middle-income countries. Numerous genetic epidemiology studies have been conducted of many ethnic groups worldwide and have highlighted the critical impact of the genetic environment on TB distribution. Many candidate genes associated with resistance or susceptibility to TB have been identified. In Morocco, where TB is still a major public health problem, various observations of clinical, microbiological and incidence distribution are …
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<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Objectives: </strong> In the present report, we aimed to investigate the impact of the coronavirus disease (COVID-19) pandemic on vertigo/dizziness outpatient cancellations in Japan. </p> <p> <strong class="sub-title"> Methods: </strong> We examined 265 vertigo/dizziness outpatients at the ear, nose, and throat department of the Nara Medical University between March 01, 2020, and May 31, 2020, during the COVID-19 pandemic in Japan. We also focused on 478 vertigo/…
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he condition that they should be used in conformity to His own perfections, which is His own law, and, therefore, our law.” On the first occasion a generous Roman Catholic nobleman present gave me £20 to have the Cardinal’s speech translated into Italian and widely circulated in Italy. I have good reason to believe that when Cardinal Manning went to Rome after the election of Leo XIII., he spoke earnestly to his Holiness on the subject of cruelty to animals generally in Italy, and especially concerning Vivisection, and that he understood the Pope to agree with him and sanction his attitude. I learned this from a private source, but his …
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Latest: June 14, 2022, 3:59 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> Pharmacist prescriptive authority continues to increase at the state level in the United States. Recently, the Idaho Board of Pharmacy (BOP) finalized regulations that expanded autonomous prescriptive authority in its state to a range of preventative care as well as acute and chronic conditions. This manuscript reviews the key decision points made by the BOP regarding drug categories included, education requirements, protocols, access to data, and use of standards of care. Overall, Idaho's approach closely reflects the medical model of regulation and may pr…
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Latest: June 14, 2022, 4:11 a.m.
<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Purpose of review: </strong> This review aims to surmise a bioethical approach to the phenomenon of cancelling patient operations. There is increasing public and political interest in the matter with a rise in the frequency of cancellations. Cancellations are emotional for patients and are difficult clinical decisions. </p> <p> <strong class="sub-title"> Recent findings: </strong> Reasons for cancellation involve patient factors and resource allocation applying t…
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<div class="abstract-content selected" id="enc-abstract"> <p> <strong class="sub-title"> Objective: </strong> Crimes against humanity by Nazi Germany led to the codification of procedures for trying medical professionals. The principles detailed in the Nuremberg Code formulated by the Allies represented their effort to prevent future excesses and embody today's Institutional Review Boards. Reactive arthritis is often termed Reiter's syndrome, after Hans Reiter, who was incarcerated at Nuremberg. </p> <p> <strong class="sub-title"> Methods: </str…
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Latest: June 10, 2022, 1:05 a.m.
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